If the pen can't respond, plug the USB cable into another USB port of your computer.
If the pen still can't respond, the hardware is defective.
If the pen can respond, go to next step.
Make sure you have completely removed any other tablet drivers in your computer, then install the latest driver of A610 from our website. https://support.parblo.com/hc/en-us/articles/360005057694-A610-Driver